YOUR TROUBLES SHOOTER PARTNER FOR THINKING CONTINUOUS (UP TO INDUSTRIAL SCALES):

• FEASIBILITY STUDIES
• PROCESS OPTIMIZATION
• IN LINE ANALYSIS (UV, RAMAN, FTIR…)
• ROUTE SCOUTING
• SMALL PRODUCTION LOTS
• PRE INDUSTRIALIZATION COSTING
• ON SITE IMPLEMENTATION

For:  

• CHEMICAL SYNTHESIS
• CRYSTALLIZATIONS
• FORMULATIONS
• SEPARATIONS
• EXTRACTIONS

Improving: 

• SAFETY
• QUALITY
• COST STRUCTURE
• ECO IMPACT

Solid know how on a wide range of flow chemistries : nitrations, oxydations, direct fluorinations (F2), NaN3 chemistries, ionic liquids, biocatalysed synthesis, very low temperature chemistries, chlorinations, polymerizations, nanoparticles

production, hydrogenations, couplings, photochemistry…

Contact us: Laurent PICHON, l.pichon@mepi.fr +(33) 06 73 99 95 31

MEPI, Plate-forme SAFRAN HERAKLES, Chemin de la Loge, CS 27813, F-31078 Toulouse, France

www.mepi.fr

NEW BOTTLE-TOP DISPENSERS - 7 MODELS, FROM 0,1 ML UNTIL 100 ML
The CalibrexTM bottle top dispensers are robust instruments with excellent chemical resistance. Intended for the safe and reproducible liquid distribution, the line includes 7 different sizes: 0.1-1 / 0.25-2.5 / 0.5-5 / 1-10 / 2.5-25 / 5-50 / 10-100 mL.

CalibrexTM organo 525 includes a ground glass or ceramic plunger, both suited for organics and non-crystallizing solutions.

CalibrexTM solutae 530 has a glass or ceramic PFA coated plunger for trouble free distribution of salt solutions, weak and strong acids and bases.

Volume setting with a spring-loaded sliding cursor softly moves up and down along dual scale. Optional flow control stopcock for priming dispenser, reagent is recycled without loss or contamination. Valves, plunger, barrel and delivery jet are removable in seconds for cleaning. Printed QR code for instant access to chemical resistance chart. Fully autoclavable at 121°C.

Access to calibration mechanism protected by safety seal sticker. Integrated key is located under plunger cap. Each dispenser with own serial number. Stringent quality control attested by an individual certificate. Two-year warranty.

www.socorex.com

OHAUS – ENSURING ACCURACY IN EVERY LABORATORY PROCESS

OHAUS manufactures an extensive line of high-precision electronic and mechanical balances and scales that meet the demands of virtually any weighing need. The company is a global leader in the laboratory, industrial, and education channels as well as a host of speciality markets, including the food preparation, pharmacy and jewellery industries. OHAUS products are precise, reliable and affordable, and are backed by industry-leading customer support. Thirty-five years ago OHAUS created the portable electronic balance market with the introduction of the Port-O- Gram balance. In 1996 OHAUS pushed the boundaries of portable weighing even further with the introduction of the Scout series. Since its introduction, the Scout has evolved with faster stabilization time, higher capacities, new features, and more applications. Its reliability, durability, precision, and flexibility to serve different markets have made it a customer and dealer favourite for twenty years. The recently introduced all-new Scout features the first touch-screen in a portable balance, fast stabilization, superior overload protection, and new connectivity options. Focused not only on portable balances, over the past several years, OHAUS presented multiple Explorer balance models, that have helped set a new definition of what modern weighing and measurement means in today’s science, research and development landscape. The newest addition to the Explorer Series, the Explorer Semi-Micro, brought the Explorer Series’ trademark ingenuity and intuition to applications requiring extreme precision, down to 0.01mg. Explorer Semi-Micro has been designed for professional use in which accuracy of results is of the utmost importance.

www.ohaus.com

SOLVAY, THE DIPHENOLS LEADER AT CHEMSPEC 2016

Solvay Aroma Performance, leader in Diphenols solutions for Pharmaceutical and Agrochemical challenges, presents its full portfolio and services at Chemspec 2016 (Basel Messe June 1-2, 2016).
Solvay showcases its leading position on the diphenol derivatives of the market (Catechol, Guaiacol, Hydroquinone among others) with high quality standards.
“We want to keep a step ahead as key supplier in this Industry by developing our customers’ intimacy & building on our global presence to ensure proximity supply, safety & services” says Vanessa Gambin, Global Diphenol Manager.

• Aroma Performance ensures key features for its diphenol portfolio used as starting raw materials for APIs ie:
• Full integrated chain mastered in Solvay sites
• Worldwide presence
• Safe & reliable quality
• Security of supply thanks to three plants around the world
• Safety & Traceability as key commitments of the Group
• High quality standards to meet Agro & Pharma demanding requirements
• Historical expertise in diphenols & patented technologies
• Dedicated technical services to develop customized solutions for our customers based on our key core technologies

“Solvay is fully dedicated to propose the best & safest solutions while offering both competitive and sustainable product” Vanessa adds. This commitment is strengthened by the Solvay unique upstream industrial integration and the strong Agro & Pharma regulation & constraints knowledge.
Solvay team of experts welcome you at the Solvay booth L54 in Hall 1.1 to further present our full range of diphenol solutions.

More information on www.solvay.com

Contacts: vanessa.gambin@solvay.com - maud.joassard@solvay.com

WORLD’S FIRST AUTOMATED FOAM ANALYSIS ACCORDING TO ROSS-MILES

KRÜSS GmbH has exhibited its new foam analysis instrument, the Ross Miles Foam Analyzer – RMFA, at Analytica 2016 in Munich. The RMFA is the world’s first instrument for measuring foam height electronically according to the ASTM D 1173 standard, which is commonly referred to for investigating the foamability of foam-forming substances. Measurements with the RMFA are distinguished by high repeatability, large sample throughput and convenient data handling. For measurements carried out in accordance with ASTM D 1173, the foam-forming solution is presented in a high, cylindrical receiver vessel with standard dimensions. A second quantity of the same solution is introduced from above by means of a likewise standardized reservoir.

This passes through the column and forms foam as a result of the turbulence on mixing with the receiving phase. The foam height is measured as soon as the reservoir is empty and also after 60, 180 and 300 seconds. Up to now, the height and time have had to be recorded manually. Results were therefore dependent on the user and were subject to a corresponding uncertainty.

With the RMFA, this is belongs to the past. www.kruss.de

EXTRACTING SCENTS AND SMELLS

Genevac evaporator systems are widely used by researchers seeking to safely extract novel fragrance molecules from natural sources. To obtain fragrances from natural products - chemists and perfumers often employ organic solvent extraction techniques to produce a large volume of crude extract. This technique is preferable to steam distillation as the higher temperatures are prone to denaturing the delicate fragrance molecules and some materials do not yield their characteristic aroma using steam. Using a patented low temperature technology, the Genevac Rocket™ vacuum evaporator has become a defacto standard for safely concentrating crude extracts while preserving delicate fragrances. To isolate individual fragrance components from the concentrated extract, one or two dimensional chromatography is then often the technique of choice. Rocket Evaporators use patented vacuum technology to evaporate solutions to dryness, or to concentrate, rapidly and safely. The latest Rocket Synergy evaporators offer integrated, flexible solutions for processing a wide range of sample volumes. Interchangeable rotors will accommodate tubes, flasks and batch volumes of up to 100 litres. To view a video that provides an overview of the Rocket evaporator, and how the system works please visit www.genevac.com/movie/rocket. For further information on the use of Genevac Evaporators in natural products research please visit www.genevac.com/en/Application.asp?S=10&V=1&Page=91 or contact Genevac now on +44-1473-240000 / +1-845-687-5000 / salesinfo@genevac.co.uk

COMPARISON OF METHODS FOR CONCENTRATING WINTERISED CANNABIS EXTRACT

Genevac has posted a YouTube™ video of a demo at California Gold Extractions (San Diego, USA) which compares use of a rotary evaporator and the Genevac Rocket Synergy evaporator, for the batch concentration of 2 litres of winterised cannabis extract in ethanol. Cannabis oil extract has been used medicinally for generations to help treat a variety of conditions, and its popularity has increased considerably in recent years. Of the various extraction methods used, ethanol extraction is increasingly becoming the method of choice because of its ability to economically and effectively produce an extract with a high terpene content that is safe for consumption. In the video interview, Jim Bilotta of California Gold describes the protocols required to batch concentrate winterised cannabis extract in ethanol using both a rotary evaporator and a Genevac Rocket Synergy evaporator. Mr Bilotta confirms the considerable walkaway automation benefits of the Rocket Synergy evaporator both in terms of freeing staff to do other tasks and reproducibly producing a top quality cannabis oil extract. Genevac Rocket and Rocket 4D Synergy evaporators set a new benchmark in evaporation versatility. Fitted with a stainless steel evaporation vessel either system can dry or concentrate batch volumes of up to 5L with no user intervention or attention. An auto-feed system on the Rocket 4D synergy extends capacity, enabling unattended automated processing of many tens of litres of product. For further operational versatility the bowl rotor may be quickly removed and replaced with a six position flask rotor to accommodate the full range of Rocket Sample handling solutions such as flasks, tubes and SampleGenie.

To watch the YouTube™ video visit https://youtu.be/vZtektLHMzM or for further information on the Rocket Synergy Evaporator contact Genevac now on +44-1473-240000 / +1-845-687-5000 / salesinfo@genevac.co.uk

DEPLOYMENT AT 4,572 METERS ABOVE SEA LEVEL

In an Indian observatory in the Himalayan mountains a Huber Unichiller maintains constant operating temperatures for measuring instruments on an astronomical telescope. The observatory is located on Mount Saraswati in the Western Himalayas, near the town of Hanle, and is operated by the Indian Institute for Astrophysics. At a height of 4,572 meters, it is one of the highest observatories in the world. The observatory has an optical 2m infrared telescope, the “Himalayan Chandra Telescope” (HCT), which is controlled remotely by the “Centre for Research and Education in Science and Technology” (CREST) near Bangalore through a dedicated satellite connection. To ensure that remote operation functions reliably, even in the winter and in the summer, a Huber Unichiller cools the instrument electronics to a consistent temperature. The constant operating temperature also prevents measurement errors caused by severely fluctuating exterior temperatures. Before installing the device in the Himalayas, a special testing chamber was built in order to simulate cooling under such extreme conditions. The low air pressure and extreme temperature fluctuations were the greatest technical challenges for the project. A Unichiller with heating was custom-built using the findings of the tests and simulations. The device is designed to function reliably even under the difficult climatic conditions.

www.huber-online.com

FLEXIBLE MICROWAVE SYNTHESIS PLATFORM

Microwave technology is changing the way to design and optimize synthetic protocols as well as their scaling up to multi-gram production!

Today microwave assisted synthesis has become a cutting-edge technology across the pharmaceutical, biotech, polymers, fine- and agro-chemical industries, with thousands of units installed worldwide.

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis devices, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high-pressure synthesis, as well as solid-phase reactions.

The new flexiWAVE microwave cavity has a volume in excess of 70 litres, by far the largest currently available. This allows the chemist to easily configure many different reactions setup in a very flexible environment. Starting from the classic synthesis glassware moving to high-pressure vessels working-alone or in parallel configuration, a large cavity is also fundamental to perform solid phase synthesis tasks. The flexiWAVE is equipped with a total of 1900 Watt making it the most powerful microwave platform system available for organic and inorganic synthesis. The system additionally employs a rotating diffuser that evenly distributes the microwaves throughout the cavity enabling very fast and homogeneous heating of samples from milli-gram to multi- gram preparations.

The new Milestone flexiWAVE is equipped with the most advanced yet easy to use reaction sensors for the most complete control of the reaction process. When performing parallel reactions, a contact- less sensor is used to control each and every vessel, and the actual temperature values are shown on the instrument control terminal, allowing an instant visual check of the reaction conditions.

www.milestonesrl.com

RECYCLABLE, SUGAR-DERIVED FOAM - A RENEWABLE ALTERNATIVE TO TRADITIONAL POLYURETHANES?

Polyurethanes in products from cushy sofas to stretchy spandex have made sitting, sleeping and walking more comfortable. But once they have served their purpose, most of the non-degradable materials pile up in landfills.

Now scientists report in the journal ACS Macro Letters a potential way to reduce future waste: a chemically recyclable foam made using a new sugar-derived material.

Polyurethanes are highly versatile materials. In addition to furniture and clothing, manufactures use them in electronics, cars, floors and medical devices. But the materials come from petroleum, and efforts to recycle them are limited. To tackle the huge amount of waste this creates, scientists are pursuing more sustainable options. Marc A. Hillmyer and colleagues developed an efficient method to make a sugar-derived rubbery polyester compound called poly(b-methyl-d-valerolactone), or PMVL, that can be used in new chemically-recyclable polyurethanes.

Using this new polymer, the researchers made flexible polyurethane foams that were comparable in performance to commercial analogs.

To test whether the foams could be recycled, the team first added a catalyst, then heated the materials to a high temperature. Through this process, the researchers recovered up to 97 percent of the starting b-methyl-d-valerolactone (MVL) monomer in high purity.

The researchers then used what they recovered to re-make PMVL with essentially identical properties.

The authors acknowledge funding from the National Science Foundation supported Center for Sustainable Polymers and the University of Minnesota Graduate School.

www.acs.org/content/acs/en/pressroom/presspacs/2016/acs-presspac-may-4-2016/recyclable-sugar-derived-foam-a-renewable-alternative-to-traditional-polyurethanes.html