The aim of this pilot study was to provide preliminary clinical data on a new line of oral hygiene products containing a prebiotic and a paraprobiotic based on Lactobacillus plantarum (efficacy on plaque and gingival sensitivity, safety and tolerability of Delicate mint and mint Toothpastes with the use of a toothbrush and a mounthwash).
The data obtained from this study will form the basis of a future larger confirmatory study on the feasibility of a standard daily hygiene model, including the use of toothpaste, mouthwash, and toothbrush marketed with the claim of improving oral prevention and protection.
In this prospective pilot study, 84 patients with a history of poor oral hygiene were enrolled in an open-label, interventional, randomized controlled clinical trial.
The screening visit was performed at the Investigator’s private dental clinic in Pavia, while the patients underwent the examinations required by the study protocol at the Complife Italia Clinical Center.
