Asynt reports how scientists at Liverpool ChiroChem (LCC) are using an Illumin8 parallel photoreactor to synthesise a range of di- and tri-functionalised N-pyrrolidines likely to be of high interest to the drug discovery community.

Since their formation in 2014, LCC have provided leading scientific organisations with access to chirally-pure compounds that play their part in small molecule drug discovery. Dr Shaun Smullen, a senior research chemist at LCC commented ” The recent introduction of Asynt’s Illumin8 parallel photoreactor has drastically improved our efficiency by allowing us to perform eight reactions simultaneously”

The Illumin8 parallel photoreactor is designed to be simple to set-up, flexible in operation and easy-to-use. It allows users to run up to eight photochemical reactions at a time in 6 mL borosilicate tubes. The unit mounts on a standard magnetic hotplate stirrer enabling powerful agitation and heating (up to 80 °C). Easy to use connectors, on top of the Illumin8, allow for an inert atmosphere or vacuum to be applied to each reaction tube. Compact in size, the Illumin8 parallel photoreactor features a ring of eight high power UV (365 nm) or blue (450 nm) light emitting diodes (LEDs) with safety interlocks to ensure light tight photochemical reactions. With each LED positioned close to a corresponding reaction tube, Illumin8 efficiently delivers an even photon flux to each reaction enhancing the consistency of your photochemical reactions.

Download white paper: www.asynt.com/wp-content/uploads/2020/02/Photochemistry-with-Illumin8-LCC-white-paper-SHARE.pdf.