Bionap S.R.L presents a recent clinical study utilizing MOROSIL™ published in Nutrients , an international advanced forum for publishing studies related to Human Nutrition.

MOROSIL™ is a standardized solid extract obtained only from the juice of a unique cultivar of Moro red oranges (Citrus sinensis (L.) Osbeck) and comes from Sicily,  this active ingredient, exhibited significant benefits for weight loss and body mass index (BMI).

The study showed that MOROSIL™ helped to accelerate weight loss and BMI by acting on waist and hip circumference. It also was able to improve body composition by decreasing fat mass. “This recent clinical study further showed the weight loss benefits of MOROSIL™ along with its ability to assist in body composition changes,” said Andrea Bonina, managing director for Bionap. “There was a significant decrease in abdominal, visceral and subcutaneous fat mass, while the lean muscle mass was kept constant.”

The study’s aim was to demonstrate the effectiveness of MOROSIL™ for weight loss, changes in BMI and body composition in overweight but otherwise healthy individuals. The study was randomized, double blind and placebo-controlled where participants received either 400 mgs of Morosil or a placebo daily for six months. Participants also maintained a calorie-restricted diet and followed a specified exercise program. MOROSIL™ is now supported by two clinical studies both exhibiting weight loss and reducing BMI along with waist and hip circumferences. Both clinical studies were randomized, double-blind, placebo-controlled studies. MOROSIL™ is a standardized extract from the juice of a unique variety of ‘Moro’ red oranges which have an intense violet-red or black color due to its high content of anthocyanins. This high content of anythocyanins contributes to its activity in reducing fat accumulation and helps to manage weight. To sum up, MOROSIL™ acts on these aspects:

• On adipocytes metabolism and differentiation because is able to modulate the adipogenesis though several key pathways in which redox homeostasis alteration is also involved together with the downregulation of adipocytespecific and lipogenic gene transcription.(In vitro studies, as scientific support);
• On the weight management because is able to reduce the body weight and the body mass index acting on waist and hip circumference in men and women.(1 clinical trial, as scientific support);
• On the boosting results of calorie restriction diet and exercise because is able to accelerate the reduction of body weight and body mass index acting on waist and hip circumference in men and women of Caucasian and Asian ethnicity. Moreover, it is able to improve the body composition (DEXA scan) by decreasing general fat mass and fat mass trunk.(1 clinical trial, as scientific support).

 For additional information about MOROSIL™, visit Bionap’s web site at: http://morosil.bionap.com/