BifiZen®: Evidence-based psychobiotic formula with high clinical promise
As holistic approach to mental wellbeing, Probiotical proposes a range of solutions associating its psychobiotic formula, BifiZen®, to well-established and clinically-backed actives to offer a range of 5 products to address different mental health benefits and to allow claims in Europe.
BifiZen® is a high-potential probiotic combination of four different strains (L. fermentum LF16, L. rhamnosus LR06, L. plantarum LP01 and B. longum 04), that were selected based on in silico, in vitro and preclinical studies. BifiZen® is characterized by anti-inflammatory and antioxidant properties, antagonism properties towards different classes of pathogens, protection and restoration of membrane integrity and other peculiar properties to benefit nervous system.
In a double-blind, placebo-controlled randomized trial, 6 weeks of supplementation with BifiZen® significantly and consistently improved several aspects of mood, with a reduction in depressive mood state, anger and fatigue, and improvement of acceptance, which correlates with decreased depression sensitivity, and sleep quality in a young and healthy cohort, which is among the most resilient population possible. The effects of the administration of BifiZen® were maintained after three weeks of wash-out, demonstrating prolonged benefits after cessation of probiotic intake.
Their faecal microbiota was sampled for subsequent analysis and was the subject of a second publication, demonstrating that daily treatment with BifiZen® significantly modified the composition of the intestinal microbiota of the subjects treated.
The unique nature of BifiZen® solutions
Bifizen® Stress and Bifizen® Focus target students and working age generations, with benefits for stress or mental performance.
Bifizen® Night benefits sleep quality and contributes to sleep duration and time to fall asleep improvement.
BifiZen® Age Well is designed for healthy ageing, to support cellular membranes and cognitive decline.
In BifiZen® Kids, a combination with anxiolytic properties, to target anxiety and insomnia.
About Probiotical S.p.A.
Born in 1985, Probiotical is an Italian family company that has distinguished itself as key player in the probiotics industry. Strong of 70 years of experience in good bacteria, Probiotical built the first plant worldwide designed exclusively for the research and production of probiotic microorganisms. It’s unique know-how goes from strains isolation all the way to the finished product, offering a broad portfolio of cutting edge, scientifically-backed probiotic bacteria both as allergen-free and microencapsulated raw materials, ready to market or tailor made finished products.
