HAIRGENYL® is an anti-hair loss active ingredient, which supports the biological activity of the dermal papilla and stimulates hair follicle growth to re-normalize hair development.
AT THE HEART OF HAIR FOLLICLE BIOLOGY
Androgenetic alopecia is the result of a deregulation of the hair growth cycle, mainly affecting men and leading to gradual hair loss.
SILAB specifically developed 2D and 3D cell and tissue models mimicking the androgenetic alopecia to identify and demonstrate the efficacy of HAIRGENYL® on the dermal papilla.
At the heart of hair follicle biology, HAIRGENYL® targets three regulators of hair growth. With HAIRGENYL®, SILAB demonstrates for the first time that increasing mitochondrial fusion boosts the capacity for energy production that is used for growth of the hair follicle [1]. Also, HAIRGENYL® corrects the abnormal expression of signaling molecules [2] and epigenetics [3] involved in androgenetic alopecia.
[1] Tested at 0.04 [2] Tested on human hair follicle dermal papilla cells treated with DHT, HAIRGENYL® at 0.04 [3] Tested on human hair follicle dermal papilla cells treated with DHT, HAIRGENYL® at 0.04
ANTI-HAIR LOSS AND REGROWTH EFFECT
Tested over 8 months on a group of male volunteers, HAIRGENYL® increases hair density (+24.9 The majority of volunteers consider their hair becomes thicker (85 By restoring the density of the hair, HAIRGENYL® is the strategy of choice for anti-loss and regrowth actions.
[4] HAIRGENYL® formulated at 0.3
100
SILAB offers a natural patented solution, developed with its expertise in biotechnologies.
Obtained from the yeast Pichia minuta, isolated from the flowers of azalea Rhododendron indicum and manufactured in SILAB’s production unit dedicated to biotechnologies, HAIRGENYL® is rich in biopeptides with low molecular weight and is the result of a nondenaturing production process.
A preservative-free powder, HAIRGENYL® (INCI name: Yeast Extract) is soluble in water, easy to formulate (recommended amount: 0.05 to 0.5