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The global high potency API contract manufacturing market size is expected to reach USD 14.65 billion by 2030, registering a CAGR of 9.0% over the forecast period, according to this report. The main drivers of this market are rising demand for oncology drugs, advancements in manufacturing technology, and a rise in capacity to meet the increasing demand. Also, a rise in target therapies to cure chronic diseases is going to accelerate industry growth. The COVID-19 pandemic boosted the demand for high potency APIs (HPAPIs). During the first half of the pandemic, the supply chain was disrupted, which reduced research-based activities.

However, during the second half, the industry started to gain importance due to a rise in demand for vaccines to fight the coronavirus. This rise has also increased the demand for raw materials and product intermediates of API molecules. Moreover, the growing demand for HPAPI molecules during the COVID-19 pandemic has led to the price hike of the same, thus boosting revenue growth in 2020 and 2021. There has been a rise in the outsourcing activities of high potency active pharmaceuticals as it removes the need for investment in expensive infrastructure for containing it.

Also, the installation & maintenance of the facility is complex and requires specialized engineers. The high cost of producing high potency API in-house, combined with the pressure to produce affordable drugs, has significantly contributed to the increasing outsourcing activities by companies. A wide range of outsourcing providers offers HPAPI services, thus making it difficult for companies to choose an appropriate CDMO. The large-scale CDMOs become the most likely choice as they provide large volumes. However, due to the small volumes required for dosage, small-scale providers are also gaining importance. 

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