The highly evolved and complex microbiota plays a crucial role in overall health: some go as far as calling the gut a “second brain”. Its optimal functionality relies on delicate balances threatened by stress, poor diet, illnesses and more. That’s why solving common issues like abdominal bloating can be so tricky. Indena’s insight was to develop a combined strategy compounding the benefits of two ingredients supported by solid scientific evidence: both in Phytosome® formulation and processed with strong commitment to sustainability, curcumin and boswellia join forces to control oxidation, bacterial balance and muscle cramps, for optimal gut health and better quality of life.
The result is a new product from Indena: CUBO™, a key help to solve abdominal bloating and enjoy a better life.
Indena’s curcumin Phytosome® offers the synergic power of the 3 major curcuminoids, naturally present in turmeric. Standardized to contain 18-22% of total curcuminoids by HPLC, its efficacy is demonstrated by 35 scientific studies involving more than 2000 subjects. The Boswellia serrata extract available from Indena is a whole natural, tested, standardized one, enriched in the whole bouquet of terpenoic acids. The triterpenoid composition of Indena’s extract includes 11 relevant boswellic acids, and closely matches the profile of the natural resin.
Both Indena’s curcumin and boswellia are formulated with Phytosome®, the proprietary 100% food-grade delivery system which exploits the power of botanicals, enhancing their physiological functions.
Recently, clinical evidences from three different studies (1) demonstrated the efficacious support given to gut health by the two Phytosome® coalition, which has been proven to provide multiple health benefits for gut easy transit, controlling bloating, abdominal discomfort and balancing intestinal microbiota.
The first study investigated the beneficial effects on abdominal bloating with the food-grade formulation of Curcuma longa and Boswellia serrata extracts in subjects experiencing irritable bowel condition and small bowel microbiota unbalance. A second human study focused on a condition mostly characterized by intermittent or persistent episodes of abdominal discomfort and by the concomitant presence of diverticula and of abdominal bloating. Recently Indena performed a third clinical study in IBS (irritable bowel syndrome) subjects with a smart, flexibile and optimized ratio combination of Curcuma longa and Boswellia serrata formulated with Indena’s Phytosome®. All the mentioned studies show that CUBO™ exercises multiple actions in favor of gut health and can be called the winning duo to free your intestine from bloating.
References and notes
- Giacosa, A.; Riva, A.; Petrangolini, G.; Allegrini, P.; Fazia, T.; Bernardinelli, L.; Peroni, G.; Rondanelli, M.. Nutrients 2022, 14, 416. https://doi.org/10.3390/ nu14030416.
Giacosa A, Riva A, Petrangolini G, Allegrini P, Fazia T, Bernardinelli L, Gasparri C, Faliva MA, Peroni G, Perna S, Rondanelli M. Drugs in Context 2020; 9: 2020-9-2. DOI: 10.7573/dic.2020-9-2. Giacosa, A. et al, under submission.
