Rousselot, Darling Ingredients’ premier collagen and gelatin brand, today announced the publication of scientific studies strengthening Peptan® collagen peptides claims in two peer-reviewed journals. These studies – a clinical trial demonstrating Peptan’s efficacy in improving skin beauty markers and a bioavailability study showcasing its effective absorption profile – provide valuable scientific insights for the nutraceutical and functional food industries. The findings will be showcased at Vitafoods Asia in Bangkok, September 18-20, 2024.

Laboratory glassware with pipette dropping fluid into test tube

Published in the Wiley Journal of Cosmetic Dermatology, the clinical study by Vleminckx et al. investigated the influence of Peptan collagen peptide supplementation on visible signs of skin beauty and aging in East Asian women aged 40-65. The trial, involving 85 participants who took 5g of Peptan daily for 12 weeks, showed significant improvements compared to the placebo group: skin density, elasticity, and hydration increased while wrinkle depth was reduced.[1]

“This study solidifies Peptan’s robust scientific foundation as a powerful ingredient for delivering evidence-based beauty solutions globally, including in Asia,” said Gaëtan Noiret, Global Director of Health & Nutrition at Rousselot.

In a second study, published in Frontiers in Nutrition, researchers from Rousselot, BioTeSys and Triskelion conducted a randomized, double-blind crossover trial to explore Peptan’s absorption profile. The study evaluated the absorption of bioactive di- and tri- peptides and free amino acids – key markers of collagen intake – from bovine hide, porcine skin and fish skin each with varying molecular weights, following consumption by healthy individuals.

Group of talented young scientists wearing rubber gloves and white coats gathered together at modern laboratory and working on ambitious research

By measuring plasma concentrations of free and peptide-bound hydroxyproline (Hyp), results showed significant levels of these metabolites.[2] Importantly, the findings indicated consistent bioavailability – defined as the portion of a nutrient or bioactive compound that can be absorbed into the bloodstream[3] – across different raw material sources and molecular weights.

“These findings further affirm Peptan’s value as an effective and bioavailable ingredient, regardless of its origin or molecular weight, underscoring its versatility for use in a wide range of product applications,” Noiret said.

Rousselot will present these groundbreaking studies at Vitafoods Asia 2024. Catarina da Silva, Rousselot’s Science Integration Manager, will discuss the findings and their implications for beauty-from-within applications and holistic well-being. Visitors can learn more about Peptan and these recent studies by visiting the Rousselot booth P10 during the event or the website.

https://www.rousselot.com/

[1] Vleminckx, S., et al, Influence of collagen peptide supplementation on visible signs of skin and nail health and aging in an East Asian population: a double blind, randomized, placebo-controlled trial, Journal of Cosmetic Dermatology, 2024;00:1–9, https://doi.org/10.1111/jocd.16458.

[2] Virgilio, N., et al., Absorption of bioactive peptides following collagen hydrolysate intake: A randomized, double-blind crossover study in healthy individuals, Frontiers in Nutrition, 11, 1416643, 2024. https://pubmed.ncbi.nlm.nih.gov/39149544/ 

[3] Ibid