During the Covid-19 pandemic period, the level of sedentary lifestyle reached records. Eating habits changed (1, 2). With documented tendencies to gain weight, the probability to get stretchmarks increased. The change in aesthetic may generate a decrease of self-esteem, and the need to have an efficient solution against stretchmarks is real yet challenging to achieve in-vivo. Another parameter affecting loss of self-esteem is the perception of skin aging, the most visible signs of which are periocular wrinkles: therefore, keeping a youthful and luminous face to renew a positive mindset gains additional relevance. The need for highly efficient anti-wrinkle effects is well and truly present. We developed a plant extract based on a poppy seed extract, RP-SE and tested it in two in-vivo studies. In the first one, RP-SE was tested for its ability to lessen the visibility of stretchmarks. In the second study, male and female volunteers with visible wrinkles on crow’s feet were recruited, and the effects of RP-SE on wrinkles and the dermis thickness were investigated. In this publication, we present and discuss the results of these two in-v ...