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Continuous-flow reactorsfor the rapid evolution and validation of kinetic motifs

corresponding

CHRISTOPHER A. HONE, RICHARD A. BOURNE, FRANS L. MULLER*
*Corresponding author
Institute of Process Research and Development (iPRD), School of Chemistry and School of Chemical Engineering,
University of Leeds, Leeds, LS2 9JT, United Kingdom

Picture on the left: Christopher A. Hone


Abstract

In this paper we apply the concept of a kinetic motif as a simple way to represent all the time-dependent behaviour in a single-step or multi-step reaction system. Small-scale continuous-flow reactors offer the potential to rapidly collect large amounts of data while accessing conventionally challenging experimental conditions. The scope of the approach is demonstrated on reaction case study examples.


 

INTRODUCTION

Continuous processing technology is transforming the way that fine chemicals are manufactured (1). Compared to batch technology, continuous-flow reactors offer many advan ... ...