In Vitro 3D human tissue models in the studies of cosmetics for “sensitive skin”
DAGMAR JÍROVÁ1, HELENA KANDAROVA2*
*Corresponding author
1. National Institute of Public Health, Department of Toxicology amd Veterinary Sciences, Prague, Czech Republic
2. InVitroTox Consulting, Bratislava, Slovak Republic
Abstract
The use of cosmetics in today’s world has a major psychosocial importance and impact on strengthening self-confidence, self‐image enhancement and social impression management. However, the world is rapidly …
The use of cosmetics in today’s world has a major psychosocial importance and impact on strengthening self-confidence, self‐image enhancement and social impression management. However, the world is rapidly changing and our body, starting with the skin, is under strong assault from indoor and outdoor pollution, sudden temperature changes in climates going from the cold, dry winds outdoors to dry heat indoors and has not yet evolved enough to neutralize these factors on its own.
The consequences range from increased skin sensitivity and irritation to premature skin aging, discoloration, dryness, dullness, roughness and even to organ damage and, at its worst, cancer. Cosmetics may offer at least some ways to protect against the damage and provide the skin repair.
The real threat often doesn’t come from particles of urban dust, ultrafine dust, diesel exhaust or cigarette smoke, but it comes from the toxic chemicals that find a way to attach to these particles. While the particles of pollution are usually too large to penetrate skin themselves, many of the chemicals attached to them are not. Those livi ...
