Mild cognitive impairment in elderly and supplementation with omega 3 fatty acids, melatonin and tryptophan: a review
MARIANGELA RONDANELLI1*, ANNALISA OPIZZI1, MILENA FALIVA1, MARCO MOZZONI1, SIMONE PERNA1, ROBERTA CAZZOLA2, RITA SAVARÈ3, ENZO GROSSI3, BENVENUTO CESTARO2
*Corresponding author
1. University of Pavia, Department of Applied Health Sciences, Section of Human Nutrition and Dietetics Azienda di Servizi alla Persona (ASP), Via Emilia 12, Pavia, 27100, Italy
2. University of Milan, Department of Clinical Sciences “L. Sacco”, via G.B. Grassi 74, Milan, 20175, Italy
3. Bracco S.p.A, Medical Department, Via XXV Aprile 4, S. Donato, 20097, Italy
Abstract
Age-related changes in nutritional status can play an important role in brain functioning. Specific nutrient deficiencies in the elderly, including omega-3 fatty acids, tryptophan, B-vitamins, and antioxidants among others, may exacerbate pathological processes in the brain. Consequently, the potential of nutritional intervention to prevent or delaycognitive impairment and the development of dementia is an important topic. The review takes into account the recentliterature on the effects of specific nutrients on cognitive function and emotions.
...
