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Obesity and overweight have reached epidemie proportions globally and it is considered to be one of the major risks for chronic diseases, such as hyperlipidemia, heart diseases, type 2 diabetes and disability. Therapeutic weight loss includes a combination of diet, exercise and sometimes weight loss drugs, but natural active substances offer a safe and effective solution and support to the reduction of body weight.

Over the last years, several studies have proven the beneficiai effect that flavonoids and polyphenolic compounds, are able to affect lipid metabolism by specific molecular actions. For example, anthocyanins were shown to ameliorate adipocyte metabolism by regulation of adipocytokine gene expression.

In particular, several in vitro and invivo studies have investigated the health-related properties of blood orange intake (especially, Moro oranges) onweight management.

In fact the Moro variety is the most brightly­ colored, with a deep red flesh.The typical red coloration of the f ...