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Always approach a reaction with an open mindset. Just as there are several potential roads that will take you from Cambridge to London or from Boston to New York, there are also several routes that will take you to a target molecule. Similarly, just as you would compare the various routes (and modes of transport) to your destination and compare them based on, for example, the distance and any roadworks that may delay you, it is also advisable to consider all the available options (and tools) to take you to your target molecule.

In this article, we would like to make use of an illustration study to highlight the benefits that may arise from exploring outside of the well-established platinum group metal (PGM) catalysis area to synthesise a particular target molecule ... ...