Abstract

Biotics are one of the newest frontiers in cosmetics. Within the class of “biotics” we find the following: prebiotics (substrate for microorganism), probiotics (live microorganism), and postbiotics (inanimate microorganism and/or their components). Their relevance arises from the fact that they appear to have a beneficial effect on the skin microbiota.

This literature review is therefore composed of: 1) a study on the prebiotic potential of galacto-oligosaccharides for skin microbiota and their incorporation into different formulations. It revealed that 5% (w/v) of galacto-oligosaccharides could stimulate S. epidermidis, while inhibiting S. aureus. 2) An evaluation of skin beneficial properties of probiotics (three Lactobacillus strains) that showed antioxidant, skin whitening, antiaging, barrier improving, and anti-inflammatory activities. 3) A 4-week clinical study of TYCA06/AP-32/CP-9/collagen derived postbiotics against Propionibacterium acnes and anti-inflammation effect around lesion area.

Scientific online resources as Pubmed and Google Scholar were used to retrieve articles of interest. To screen for the most advanced research, articles were selected from the year 2022 with the following keywords: prebiotics, probiotics, postbiotics, cosmetic.

Prebiotic effect of galacto-oligosaccharides on the skin microbiota and determination of their diffusion properties

Anja Petrov1, Marija Ćorović2, Ana Milivojević1, Milica Simović2, Katarina Banjanac1, Rada Pjanović3, Dejan Bezbradica2

Affiliations:

Innovation Center of Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.
Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.
Department of Chemical Engineering, Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.

Abstract

Objective: Recently, prebiotics are attracting plenty of attention in the field of skin care, since it is found that they are able to support the balance of beneficial and harmful microorganisms on the skin, and accordingly prevent several skin conditions associated with microbial imbalance. Topical application of prebiotics, although insufficiently investigated, holds great promise in improving skin health. The purpose of this research was to determine the prebiot ...