DORIEN STALJANSSENS^1,2*, GUY SMAGGHE¹, JOHN VAN CAMP²
*Corresponding author
1. Ghent University Department of Crop Protection, Faculty of Bioscience Engineering Coupure Links 653 Ghent, Belgium
2. Ghent University Department of Food Safety and Food Quality, Faculty of Bioscience Engineering Coupure Links 653 Ghent, Belgium

KEYWORDS: Cholecystokinin; satiety; protein hydrolysates; bioactive peptides; CCK1 receptor.
ABBREVIATIONS: CCK: cholecystokinin, CCK1R: cholecystokinin receptor type 1
ABSTRACT: Cholecystokinin (CCK) is a gut hormone that induces a feeling of satiety and therefore plays an important role in weight regulation. In this minireview, different food proteins and protein hydrolysates will be introduced that are able to enhance CCK-mediated satiety. This mechanism can be influenced at three interaction points, namely CCK release, trypsin-sensitive luminal CCK-releasing factors and the CCK receptor. Food components able to affect satiety are very promising ingredients in the development of functional foods that can be used as an aid in the battle against obesity.

INTRODUCTION
Weight maintenance and appetite regulation in vertebrates is a complex process in which different mechanisms are involved (1). In the recent decades, these mechanisms and their potential interaction points have gained a lot of attention since the prevalence of obesity keeps on rising (2). One important weight maint ...
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