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EDITORIAL
Pharmaceutical sciences and the opioid crisis
A.Coop
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COVER STORY
Piramal – Biocatalysis: From academic curiosity to manufacturing mainstream – the emergence of enzymes as catalysts in API manufacture
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News
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A WORD WITH
Dr. Aslam Malik, CEO – AMPAC Fine Chemicals
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A WORD WITH
Stefan Lander – Vice President Consumer Goods Sales & Marketing – OMYA
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A WORD WITH
Didier Combis Director B.U. Exclusive Synthesis & PharmaChemicals – PCAS
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PHARMACEUTICAL CHEMISTRY: APIS - HPAPIS
Development and implementation of a large-scale HPAPI manufacturing process
I. Grayson, J. Becker, T. Pohlmann, K. Blumbach, K. Mccleary, M. Van Hoosier
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COMPANY PROFILE
SK Biotek – SK announces opening of their new, state-of-the-art API manufacturing facility
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PHARMACEUTICAL CHEMISTRY: APIS - HPAPIS
Medicinal mechanochemistry: from solid form screening to cleaner and safer synthesis of active pharmaceutical ingredients
T. Friščić
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A WORD WITH
Stefano Martinoli, Member of the Board – Munit
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PHARMACEUTICAL CHEMISTRY: APIS - HPAPIS
Metal-free, Stereoselective in batch and in flow synthesis of pharmaceutically relevant chiral amines
M. Benaglia
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COMPANY PROFILE
Corden Pharma – Oligonucleotides: Promising Therapeutics with Significant Challenges
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PHARMACEUTICAL CHEMISTRY: APIS - HPAPIS
Iterative stochastic elimination for discovering hits and leads
S. El-Atawneh, A. Goldblum
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A WORD WITH
Marianne Späne – Executive Vice President Global Business Development, Marketing and Sales – Siegfried
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COLUMN: EMERGING VALUE CHAIN
The bio-based transition: drop-in versus new products (2)
G. J. Gruter
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PRODUCT FOCUS
Ypso Facto – Streamlining process development with simulation software tools Interview of Roger-Marc Nicoud, President of Ypso-Facto®
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PHARMACEUTICAL CHEMISTRY: APIS - HPAPIS
Crystallization of a penta-peptide API and its absolute structure confirmation using synchrotron radiation
G. Steinfeld, G. Santiso-Quinones
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A WORD WITH
Jean-François Hoeffler President at Alsachim and Björn-Thoralf, Erxleben Senior Manager Marketing Europe – Shimadzu Europa
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ANALYTICAL TECHNOLOGY
Identification of surface impurities and particles by means of special analysis methods
G. Dallmann
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PRODUCT FOCUS
Arkema – Bromotrifluoromethane, a useful synthon for trifluoromethylation
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ANALYTICAL TECHNOLOGY
Synthetic polymeric resins in downstream processing for food, fine chemicals and pharmaceuticals
A. Basso, B. Summers, S. Serban, C. Bresner
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A WORD WITH
Oliver Briel – Director Global Business Electronics, Christophe Le Ret – Global Marketing Director and Denis Goffaux Chief Technology Officer
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PROCESS DEVELOPMENT
Process performance evaluation in pharmaceutical manufacturing operations
D. J. Spielvogel, H. Farouk, E. J. Bergner
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COLUMN: BIOMATERIALS & NANOMATERIALS
Making APIs and fine chemicals with light
M. Pagliaro
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PRODUCT FOCUS
Sabinsa – “Chiral Pool” Approach for enantiomeric intermediates: a powerful, simple, and economic solution
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SUSTAINABILITY/GREEN CHEMISTRY
Biocatalytic dearomatisation of para-fluorobenzoic acid – Access to versatile homochiral building blocks with quaternary centres
T. J. Nash, S. Wharry, T. S. Moody, S. E. Lewis
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COLUMN: MARKETPLACE
API industry snapshot
M. Bowman
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REGULATORY
Last leg of REACH registration is just around the corner
C. Musset
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Events